Ischemia, hyperemia, exercise, and nitric oxide. Complex physiology and complex molecular adaptations.
نویسندگان
چکیده
منابع مشابه
Ischemia, hyperemia, exercise, and nitric oxide. Complex physiology and complex molecular adaptations.
Since its discovery by Furchgott and Zawadzki in 1980,1 endothelium-derived relaxing factor (EDRF) has been shown to play a central role in the cardiovascular system.2 This endothelial product is chemically equivalent to nitric oxide (NO)3'4 or a biochemical congener thereof,5 and relaxes vascular smooth muscle in association with activating guanylyl cyclase and increasing cGMP. Operating throu...
متن کامل2556 Editorial Ischemia , Hyperemia , Exercise , and Nitric Oxide Complex Physiology and Complex Molecular Adaptations
Since its discovery by Furchgott and Zawadzki in 1980,1 endothelium-derived relaxing factor (EDRF) has been shown to play a central role in the cardiovascular system.2 This endothelial product is chemically equivalent to nitric oxide (NO)3'4 or a biochemical congener thereof,5 and relaxes vascular smooth muscle in association with activating guanylyl cyclase and increasing cGMP. Operating throu...
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Only recently we can link thermogenesis, mitochondria, nitric oxide, and redox regulation in biochemical terms. Currently, we are discussing these processes from the aspect of fundamental principles of molecular physiology. Thus, the present article highlights both cell physiology and the principles of the maintenance of energy homeostasis in organisms. Energy homeostasis means much more than s...
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2-Benzylaminopyridine (HBAP) reacts with NaH in THF and generates the sodium salt (NaBAP). Further reaction of [Cu(TMEDA) ] [CuCl ] with one equivalent of this ligand in THF leads to the formation of a dimeric Cu(1) complex, [Cu (BAP)] . H 0. The molecular structure has been determined by using a single-crystal X-ray diffraction method. The yellow compound crystallizes in the monoclinic s...
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هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
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ژورنال
عنوان ژورنال: Circulation
سال: 1994
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.90.5.2556